The relationship between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, although few of them have assessed the risk of all-cause mortality, which has never been evaluated in an adult Mediterranean population with a high cardiovascular risk. A recent study published in the American Journal of nutrition assessed the association between magnesium intake and CVD and mortality risk in a Mediterranean population at high cardiovascular risk with high average magnesium intake. The study included 7,216 men and women aged 55-80 y from the PREDIMED (Prevenci?_n con Dieta Mediterr??nea) study, a randomized clinical trial in Spain. Participants were followed for nearly ten years and took part in yearly follow-ups and multiple questionnaire style health evaluations. All participants were deemed to be at high risk for cardiovascular problems at the baseline of the study; they had type 2 diabetes and three or more of the following risk factors: 1) a family history of premature CVD, 2) overweight or obese, 3) smoking, 4) hypertensive and/or 5) hypercholesterolemia. Participants were assigned to 1 of 2 Mediterranean diets (supplemented with nuts or olive oil) or to a control diet (provided advice on a low-fat diet). Mortality was determined by accessing the National Death Index and medical records. Statistical analysis was used to assess the associations between yearly repeated measurements of magnesium intake and mortality. Using a food frequency questionnaire, the researchers assessed the participants?? dietary magnesium intake at baseline. The participants also reported their physical activity, history of illness, and medication use, amongst other information. Waist circumference, weight and height were measured, and blood pressure was taken. After a mid-study follow-up of 4.8 y, 323 total deaths, 81 cardiovascular deaths, 130 cancer deaths, and 277 cardiovascular events occurred. Energy-adjusted baseline magnesium intake was inversely associated with death from cardiovascular disease, cancer, and all-cause mortality. Compared with lower consumers, individuals with the highest levels of magnesium intake had a 34% reduction in mortality risk. According to this study in a Mediterranean population, magnesium is able to reduce the risk of cardiovascular disease in those who are at high risk. Magnesium is an essential nutrient which has been proven to improve health status in several different populations. AOR currently offers the following magnesium containing products: Cardio Mag 2.0, Mag-K-Taurine, Mag Malate Renew, Mag/Potassium Aspartates and Magnesium + Taurine. AOR has ALSO formulated a new comprehensive magnesium product which will be available in June, 2014, called Advanced Magnesium Complex, which contains four forms of magnesium designed to meet the body??s magnesium needs. Reference: Guasch-Ferr? M et al. Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. J Nutr. 2014 Jan;144(1):55-60. doi: 10.3945/jn.113.183012. Epub 2013 Nov 20.
Study Shows That Magnesium Reduces the Risk of Death from Cardiovascular Disease