Product Details

STRONTIUM SUPPORT II

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Supports Bone Mineral Density
  • Strontium is a mineral similar to calcium that helps build bone
  • Reduces the risk of fractures
  • Clinically effective dose & safe for long-term use
  • AOR was the first in the world to deliver strontium citrate

Use this product for:

Strontium is an important mineral for bone health and it is found in most foods where calcium is found. In 2002, AOR introduced the world’s first supplemental strontium citrate for those with osteoporosis, osteopenia, post-menopausal women and those at an increased risk of bone fractures. AOR’s Strontium Support II comes in two sizes and provides an effective dose of this bone health powerhouse in a convenient two capsule-a-day formula. 

Strontium is a mineral that actually helps rebuild bone. While supplements like calcium, vitamin D and vitamin K maintain bone health, and conventional bone drugs reduce bone degradation, strontium actually increases osteoblast production while decreasing osteoclast production, resulting in increased bone development and decreased bone loss. Since strontium is similar in molecular structure to calcium, it is thought to activate the calcium receptors in the bone, stimulating the building of new bone and telling the body to use calcium effectively in bone tissue, while inhibiting bone breakdown. A recently published study showed that strontium was not only safe to take over the course of 10 years, but also that it continued to reduce the risk of osteoporotic fractures throughout this time period. Strontium Support II is an excellent addition to calcium supplementation for those with osteoporosis or osteopenia, post-menopausal women or those at an increased risk of bone fractures.  

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Discussion

Strontium is a trace mineral which concentrates in the skeletal system, where it supports the function of osteoblasts (the cells which form new bone) while reducing the differentiation and activity of osteoclasts (the cells which resorb old bone). Strontium Support II helps support bone mineral density.

Product Variations

NPN Product Code Size
80039461 AOR04161 60 VEGI-CAPS
80039461 AOR04204 120 VEGI-CAPS

Supplement Facts

Amount Per Serving Amount: 1 Capsule
341 mg Strontium (citrate)
Non-medicinal ingredients: Capsule: hypromellose.

AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Suggested Use:

(Adults 50 years and older): Take 1 or 2 capsules daily on an empty stomach, at least two hours before or after consuming food, calcium or milk since these can significantly reduce strontium absorption if taken together. Ensure an adequate daily intake of calcium and vitamin D.

Cautions :

May cause temporary transient increases in levels of creatine kinase that are unassociated with any disorder. Discontinue use and consult a health care practitioner in case of rash or hypersensitivity, as this may be a sign of a serious allergic reaction (DRESS or Stevens-Johnson syndrome). Consult a health care practitioner for use beyond 6 months. Pregnant and breastfeeding women, those who have or are at high risk for blood clots (e.g. if you are temporarily or permanently immobilized, over the age of 80, taking birth control pills, etc.), heart diseases and/or circulatory problems (e.g. Venous Thromboembolism (VTE), heart attack, peripheral arterial disease, stroke, high blood pressure, hyperlipidemia, diabetes, etc.), or have kidney disease must not use this product. 

Pregnancy/Breastfeeding :

Source:

Pharmaceutical synthesis

Main Applications:

  • Bone health
  • Osteoporosis
  • Osteopenia
  • Increases bone density
  • Reduces risk of fractures

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

Age-Related Bone Loss Bone loss accelerates suddenly in menopausal women because the drop in estrogen levels causes an increase in the resorption (teardown) of existing bone. But resorption is only half of the story. Age-related bone loss is also caused by a decrease in the formation of new bone tissue. Strontium: The First Bone-Building Supplement! Strontium is a mineral that is able to inhibit bone resorption while simultaneously stimulating bone growth. This effect appears to be due to strontium's ability to actually increase the production of bone-building cells (osteoblasts) and decrease the production of bone-destoying cells (osteoclasts), shifting the balance toward bone growth. This is a remarkable benefit provided by taking strontium as a supplement, and no other natural substance or drug is known to provide this dual effect. People who are concerned about preserving and regaining healthy bones
Current Bone Health Options Existing drugs for treating osteoporosis work by reducing bone resorption. But they do not support the formation of new bone. These drugs reduce the rate of bone breakdown, but they do not help the body to build new bone tissue. In fact, within weeks of starting use of antiresorptive drugs like Fosamax,
In 2002, AOR was the first company in the world to produce supplemental strontium citrate.
Strontium Ranelate Most of the clinical studies that found strontium effective for reducing fractures and increasing bone density were done using strontium ranelate. This form of strontium is a prescription drug used in Europe with excellent results and minimal side effects. However, the "ranelate" portion of this salt form of strontium is inactive; only the strontium produces physiological benefits. The use of strontium ranelate allowed a patent to be developed to protect this amazing discovery. Studies using other forms of strontium are few, but they do exist and also show pronounced effects against bone degeneration, showing that strontium is the important molecule. In a study using strontium ranelate, BMD showed an increase continuously over 10 years in osteoporotic women. The incidence of vertebral and nonvertebral fracture was lowered between 5 and 10 years than in a matched placebo group over 5 years. Therefore, the results proved that Strontium ranelate's antifracture efficacy appears to be maintained long term. Another study investigated bone microstructure changes as a target in osteoporosis treatment to increase bone strength and reduce fracture risk. 83 postmenopausal women with osteoporosis were given a dosage of 2g per day of strontium ranelate for a two year period. The double-double blind exploratory trial observed both bone mineral density and bone turnover markers. Distal tibia bone microstructure was assessed by high-resolution peripheral quantitative computed tomography. Both both density and bone thickness were shown to have increased
ATSDR. Toxicological profile for strontium. Atlanta,GA: Agency for toxic substances and disease registry US Dept of Health and Human Services. Public Health Services.2001 Comar,CL , Wasserman, RH and Nold, NM. Strontium-Calcium discrimination factors in the rat. Proc. Sco. Exp. Biol. Med.1950;92:859-863 Dahl, SG et-al. Incorporation and distribution of strontium in bone. Bone.2001;28:446-453 Della Rossa et-al. Absorption and retention of ingested strontium and calcium in beagles as a function of age. Nature.1965;205:197-198 Leeuwenkamp,OR et-al. Human pharmacokinetics of orally administered strontium. Calcif. Tissue Int. 1990;47:136-140 Marie,PJ et-al. Effect of low doses of stable strontium on bone metabolism in rats. Mineral Electrolyte Metab. 1985;11:5-13 Marie,PJ et-al. Mechanisms of action and therapeutic potential of strontium in bone. Calcif. Tissue Int.2001;69:121-129. Matsumoto, A. Effect of strontium chloride on bone resorption induced by prostaglandin E2 in cultured bone. Arch. Toxicol. 1988;62:240-241 McCaslin FE and Janes, HM. The effect of strontium lactate in the treatment of osteoporosis. Proc. Mayo Clinic. 1959;34:329-334 Shorr, E and Carter, AC. The value of strontium as an adjuvant to calcium in the mineralization of the skeleton in osteoporosis in man. Conference on Metabolic Interactions. Eds. EC Reifenstein Jr.,NY.NY.Pub J Macy Foundation 1950 pp144-154. Sips, AJAM et-al. Intestinal absorption of strontium chloride in healthy volunteers: pharmacokinetics and reproducibility.Br. J Clin Pharmacol. 1996;41:543-549 Sips, AJAM.Absoption kinetics of strontium and calcium in human and experimental animal. Ph.D Thesis. University of Amsterdam. 1994 Skoryna, SC. Effects of oral supplementation with stable strontium. Can Med J. 1981;125:703-712 Skoryna, SC.Metabolic aspects of the pharmacologic uses of trace elements in human subjects with specific references to stable strontium. Trace Subst. Enviorn Health.1984;18:3-23 Skoryna,SC and Fuskova, M. In: Skoryna, SC ed. Handbook of stable strontium.NY;Plenum:1985.p593-617 Storey,E. Strontium "rickets" bone calcium and strontium changes. Austral.Ann. Med. 1961;10:213-222

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