Breaking News
B-Vitamins Help Protect Against Age-Related Macular Degeneration |
March 5, 2009 |
Age-related macular degeneration (AMD) is the leading cause of vision loss among older individuals. About 1.75 million Americans suffer from advanced AMD and another 7.3 million show early signs of this condition. Recent research has shown a direct link between blood homocysteine levels and the risk of AMD. This has led researchers to examine whether supplementation with B-vitamins, which have been shown to lower homocysteine levels, could help to prevent the development of AMD.
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Calcium Reduces the Risk of Colorectal Cancer |
February 26, 2009 |
There is no question that calcium is essential for the maintenance of healthy bones, however, the role calcium and dairy food intake in cancer is much less certain. A large-scale study published in the Archives of Internal Medicine has helped to clarify this role, suggesting a relationship between higher calcium intake and a lower incidence of colorectal and other digestive cancers.
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Nattokinase for Alzheimer’s ? |
February 24, 2009 |
Nattokinase is an enzyme extracted from natto, a soy-derived fermented food condiment popular in Japan, and is used in the preventative health field as a natural anti-coagulant and fibrinolysis enhancer. Due to this biological function, nattokinase has also been used to stabilize blood pressure. However, scientists from Taiwan claim to have discovered a new role for nattokinase, namely as a possible defense against the threat of Alzheimer’s disease.
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Cranberry Extracts Linked To Possible Colon Cancer Prevention |
February 20, 2009 |
A new Canadian study from the University of Prince Edward Island has established a connection between cranberry extract (as well as one of its derivative flavonoids, quercetin) and the expression of certain inflammatory variables linked to prostate cancer. The variables include cyclooxygenase-2 (COX-2), a central inflammatory enzyme.
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Vitamin K2, but not K1, Effective for Heart Health |
February 18, 2009 |
For every increase of 10 micrograms in the amount of vitamin K2 consumed daily, the risk of developing coronary heart disease (CHD) drops by 9 percent. This somewhat stunning statistic was noted as a result of a recent cohort study from the Netherlands evaluating the dietary vitamin K intakes of 16,057 post-menopausal women and their association with the incidence of CHD.
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New Research Establishes a Genetic Link between Vitamin D Deficiency and MS |
February 17, 2009 |
Multiple sclerosis (MS) is a debilitating neurological disease affecting over 2 million people worldwide. A number of past studies have provided epidemiological evidence suggesting that low levels of vitamin D are linked to an increased risk of multiple sclerosis (MS). Researchers at Oxford University and the University of British Columbia have now established a link between certain genes associated with MS susceptibility and vitamin D.
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Lignans Linked to Leaner and Healthier Women |
February 13, 2009 |
Lignans, first and foremost, are phytoestrogens that occur naturally in such foods as flax seed, whole grain cereals, berries, vegetables and fruits, and are metabolised in the colon by microflora into enterodiol and enterolactone. Previous research has focused on plant lignans reducing the risk of prostate cancer in men and improving menopausal health among women. However, a new Canadian study from the University of Laval in Québec has now demonstrated that women with high blood levels of lignans are also more likely to have a more ideal bodyweight and a healthier response to the hormone insulin.
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Girl Power Linked To Vitamin D? |
February 11, 2009 |
Adolescent girls may be able to increase their power by ensuring that they receive adequate levels of vitamin D, according to a very recent British study. The study is the latest among a recent plethora of clinical trials either emphasizing the importance of this hormonal vitamin, or highly recommending a significant revision upward in its respective recommended daily intake. This particular study falls under the auspices of the former, and the power it refers to is the explosive physical power generated by the muscles – in this case of young girls between the ages of 12 and 14.
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Omega-3’s and Women’s Health Part 2 – EPA reduces depressive symptoms |
February 9, 2009 |
The good news for omega-3 fatty acids and EPA (eicosapentaenoic acid) in particular continues to grow. Recently EPA has been linked to a reduced frequency of hot flashed in menopausal women, and now, two separate studies have reported that EPA may be beneficial for reducing depressive symptoms in women.
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Astaxanthin and Hypertension: The Inverse Relationship Grows |
February 4, 2009 |
Astaxanthin is a carotenoid of relatively recent discovery whose biological activity has captured the interest of scientists and preventative health experts the world over. This activity includes specific antioxidant functions that are about 550 times greater than those of vitamin E, 800 times greater than coenzyme Q10, 75 times greater than alpha lipoic acid, 40 times greater than beta-carotene and 6000 times greater than vitamin C. Astaxanthin has been studied for its applications to ocular (eye) health, type II diabetes, gastro-intestinal health, obesity, endurance and even skin health.
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Omega-3’s and Women's Health Part 1 – EPA reduces the frequency of hot flashes |
February 3, 2009 |
Hot flashes are the most common symptom reported by menopausal women. Hot flashes affect between 4 and 46% of women during early menopause, between 33 and 65% in the later stages, and 79% of post-menopausal women. New findings suggest that the omega-3 fatty acid EPA (eicosapentaenoic acid) can help reduce the frequency of hot flashes.
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Green Tea may Reduce Breast Cancer Risk |
January 30, 2009 |
Polyphenols in green tea have been shown to have wide-ranging health benefits. Data from some epidemiological studies as well as animal studies suggest, for example, that green tea may help prevent certain types of cancer, including breast cancer. A recent study published in the Journal of Nutrition provides further support for the potential benefits of green tea drinking and breast cancer prevention.
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Vitamin D linked to Cognitive Function |
January 28, 2009 |
That’s right. Some more good news for vitamin D. Results from a recent study including over 1700 elderly individuals suggest that those with higher levels of vitamin D have a reduced risk of cognitive impairment.
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Vitamin D Helps Prevent Placental Infections |
January 23, 2009 |
It seems that vitamin D is good for just about everything. Recent scientific studies have linked deficiencies of this all-important vitamin to increased fractures, auto-immune disorders, neurological diseases, skin conditions and even an increased risk of death. New research conducted at UCLA brings to light the importance of vitamin D in pregnancy, and the key role it may play in the prevention of placental infections.
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Green Tea Improves Exercise-Induced Weight Loss |
January 21, 2009 |
The health benefits of drinking green tea have been making a lot of headlines lately. There is a body of evidence to suggest that individuals consuming large amounts of green tea live longer, develop less cancer, have healthier cholesterol levels and have a lower incidence of cardiovascular disease. New research suggests that green tea may also benefit those seeking to lose weight through exercise.
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More Evidence of AHCC’s Immune Boosting Properties |
January 16, 2009 |
Recent research has shown that AHCC (a blend of various mushroom extracts) has impressive effects on the immune system. AHCC has been shown to help the body fight infections, viruses, inflammation and even cancer. A new study provides new information about AHCC’s mechanism of action, showing that it improves the number and function of key immune cells called dendritic cells (DCs), in humans.
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More Evidence for Pomegranate’s Role in Preventing Prostate Cancer |
January 8, 2009 |
Pomegranate extract contains many polyphenols, including ellagic acid, which is a powerful antioxidant linked to numerous beneficial health effects. Several past studies have provided evidence suggesting that pomegranate extracts may help to prevent prostate cancer. A new study further supports these findings, and suggests that pomegranate’s anti-prostate cancer activity may be due to direct action on genes.
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Cranberry Extract Similar to Antibiotics for the Prevention of UTIs |
January 6, 2009 |
Urinary tract infections are one of the most common types of bacterial infections, and recurring UTIs are especially common in older women. Recurrent UTIs are most often treated with antibiotics, and research has shown that a long-term treatment with a low dose of antibiotics is quite effective at preventing UTIs. Cranberry extract is another option for the prevention of UTIs. Recent research suggests that cranberry extracts are nearly as effective as antibiotics for the prevention of recurring UTIs, with fewer side effects.
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EPA better than DHA for Inflammation Associated with Asthma |
December 24, 2008 |
The general health benefits of omega-3 fatty acids are well known. However, not all omega-3’s are the same, and which fatty acids are best for certain conditions remains less certain. For example, the fatty acids EPA (Eicosapentaenoic acid) and DHA (Docosahexaenoic acid) have both been examined for their potentially beneficial effects in inflammatory conditions such as arthritis, IBS and asthma. Recent research has shown, however, that EPA in particular, may have better anti-inflammatory actions in asthma than DHA.
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Vitamin K May Reduce Insulin Resistance in Older Men |
December 23, 2008 |
The benefits of vitamin K to cardiovascular and skeletal health are well known; however, new research seems to suggest that this key vitamin may also have a positive effect on insulin resistance. Insulin resistance occurs when cells no longer respond to normal insulin levels in the blood, and thus do not take up glucose from the blood. Insulin resistance is associated with the onset of type 2 diabetes.
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Support for the Use of Hyaluronic Acid for Joint and Skin Health |
December 18, 2008 |
Hyaluronic acid (HA) is a compound that is found in high concentrations in the synovial fluid (the fluid that surrounds and cushions joints) and in the skin. Because of this, HA is a commonly used supplement to support both joint and skin health. However, HA is a fairly high-weight molecule and there is some debate over whether or not orally consumed HA is effectively absorbed into the blood stream and taken up by the tissues. A new study provides evidence that orally supplemented HA does in fact reach the skin and connective tissues.
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Vitamin D Important for Diabetics |
December 16, 2008 |
A recent study published in the Journal of Pediatrics has shown that a surprising number of young diabetics do not have sufficient vitamin D levels, suggesting that supplementation with this critical vitamin may be especially important for these individuals.
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High-Dose Vitamin B1 Could Help Prevent Diabetic Kidney Problems |
December 11, 2008 |
Recent research supports a key role of vitamin B1 (in the form of thiamin, or the more bioavailable benfotiamine) in helping to reduce the risk of a variety of diabetic complications, including nerve damage and vascular disease. In diabetics, plasma levels of vitamin B1 are very low, about 75% lower than in non-diabetic individuals – making supplementation with this essential nutrient very important. A newly published study has now linked high-dose thiamin supplementation with reduced kidney damage in Type II diabetics.
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I3C Reduces Tobacco-Smoke Induced Lung Tumors in Mice |
December 9, 2008 |
Indole-3-Carbinol (I3C) is a compound found in cruciferous vegetables like broccoli. Several mouse models have shown that I3C can effectively inhibit tumor formation. A recent study has added to this body of evidence, showing that supplementation with I3C significantly reduced the formation of lung tumors in mice exposed to tobacco-smoke carcinogens.
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Omega-3’s Reduce Oxidative Stress Caused by Air Pollution |
December 3, 2008 |
As air pollution becomes an increasingly common problem understainding the effects of exposure to particulate matter (PM) in the air is becoming an important area of research. Evidence has shown that environmental exposure to PM is associated with increased cardiovascular mortality and reduced heart rate variability (an indicator of cardiac regulation) in the elderly. The negative effects of PM are thought to be associated with increased inflammation and oxidative stress. New research suggests that supplementation with Omega-3 polyunsaturated fatty acids helps to alleviate the negative effects associated with PM exposure.
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Macular Degeneration Associated with Sunlight Exposure and Antioxidant Levels |
November 28, 2008 |
Recently, a large study called the European Eye Study was conducted to examine the combined effects of sunlight exposure and antioxidant levels on the rate of occurrence of Age-Related Macular Degeneration (AMD). The study found that there may be an important link between these factors.
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Chondroitin Sulfate and Osteoarthritis: More Support for its Positive Effects |
November 25, 2008 |
Chondroitin sulfate is a naturally occurring component present in the matrix of the cartilage of the joints. Supplementation with this compound has been widely studied for its effects on lessening the symptoms of osteoarthritis. Many studies have shown that chondroitin sulfate is effective in relieving joint pain and improving mobility in patients with osteoarthritis of the knee. A recent meta-analysis has provided further support for chondroitin sulfate’s role in battling osteoarthritis by showing that it may also have structure-modifying effects, resulting in a reduced rate of joint space loss.
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Phytochemicals in Grapes Reduce Heart Damage caused by High Blood Pressure in Rats |
November 21, 2008 |
It is well know that a diet rich in fruits and vegetables is good for your overall health and also for the health of your heart. However, new research suggests that the phytochemicals found in fruits such as grapes may play an especially important role in maintaining healthy blood pressure levels and preventing damage to the heart.
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Extracts from Green Tea Help Lower Several Cardiovascular Risk Factors |
November 19, 2008 |
Drinking tea has been linked to a wide range of health benefits, including improved cardiovascular health. However, many of the studies conducted have been solely observational, with no way of assessing the quantities of different component s of the tea. A recent randomized, double-blind, placebo-controlled study examined the effects of a standardized green tea extract on various cardiovascular risk factors.
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Low Levels of Vitamin B12 Increase the Risk of Brain Atrophy in the Elderly |
November 13, 2008 |
Vitamin B12 is extremely important for the proper functioning of the brain and nervous system. Unfortunately, deficiencies are quite common, especially among the elderly. This is an important concern, as elderly populations are especially at risk of developing cognitive disorders like dementia and Alzheimer’s disease. A new study suggests that vitamin B12 levels are associated with brain volume loss in the elderly, and may be an important factor in identifying individuals at risk of developing more serious cognitive problems.
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New European Study Shows Multi-vitamins/minerals Can Improve Children’s Brain Function |
November 6, 2008 |
A collaborative effort by British, Swiss and Australian scientists and specialists has revealed that 12 weeks of daily multi-vitamin/mineral supplementation can improve the attentiveness of elementary school-aged children, according to the results of attention test scores published in the British Journal of Nutrition.
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Ginkgo Helps Prevent Stroke Damage in Mice |
November 5, 2008 |
Ginkgo biloba extract is well known for its health benefits, especially in the brain. It has been shown to improve brain circulation and also has antioxidant properties. A new study published in the journal Stroke has shown that supplementation with a standardized ginkgo extract helped reduce neurological damage in mice following a stroke. It also provides new information regarding the mechanism of action of ginkgo in the brain.
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Whey Supplements Stimulate Protein Production during Bed Rest |
October 31, 2008 |
Whey protein is known to have a wide variety of health applications. Besides having immune boosting, anti-inflammatory, anti-microbial and other effects, whey protein has also been studied for its potential value in exercise and muscle building. A recent study observed whey protein’s ability to stimulate protein synthesis during physical inactivity.
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Resveratrol May Protect the Liver from Alcohol |
October 29, 2008 |
Alcoholic fatty liver disease is an umbrella term used to describe a number of hepatic (liver) conditions which, at their root, can be traced to an unhealthy accumulation of fatty acids in the liver caused by the excessive consumption of alcohol. Resveratrol is a highly ubiquitous phyto-micronutrient found under the skin of grapes used to make red wine, and has become increasingly pervasive as a source of research for longevity, cancer prevention and a host of other fields.
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Quercetin helps prevent influenza infection following stressful exercise in mice |
October 27, 2008 |
Severe exercise training has been shown to affect the immune system, thereby influencing the body’s susceptibility to infection. More specifically, exercise stress has been hypothesized to increase the risk of acquiring an upper respiratory tract infection. Many studies have attempted to find a nutritional strategy to counter-act this increased risk. Supplementation with quercetin is one of these strategies. Quercetin is a flavonoid present in a wide variety of fruits and vegetables, and it has been shown to have anti-viral activity in vitro. This makes it a promising candidate for helping reduce the risk of influenza infection following stressful exercise.
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Vitamin D and Eczema: Protection from Skin Infections |
October 20, 2008 |
New research suggests that vitamin D may help to prevent skin infections in people suffering from atopic dermatitis. Atopic dermatitis is a form of eczema, and is a chronic skin condition affecting 10-20% of children and 1-3% of adults. Individuals with atopic dermatitis have an increased risk of acquiring a wide range of skin infections. This increased infection risk has been linked to a defect in the immune system leading to a decreased ability to produce certain important anti-microbial proteins like cathelicidin. These proteins are normally present in wounded and injured skin and help prevent infections.
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Parkinson’s Prevention: Another Round for Vitamin D ? |
October 15, 2008 |
Insufficient levels of Vitamin D may be linked to Parkinson’s disease, according to the results of a recent observational study conducted in the southeastern United States. The study examined levels of the hormone 1,25-dihydroxyvitamin D (1,25(OH)2D), which is the final stage of vitamin D metabolism, in three distinct groups of subjects.
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Chromium Picolinate May Aid Weight Loss by Decreasing Food Intake |
October 14, 2008 |
The prevalence of obesity in western countries has risen dramatically over the past 25 years. Due to the large number of life threatening health problems associated with obesity, there is an increasing demand for dietary supplements to assist weight loss. Unfortunately, although there are many such supplements available, the majority of them have very little real scientific evidence to back up their claims. Chromium picolinate (CrPic) has been purported as an effective aid for weight loss in overweight individuals and has been shown to slow down weight gain. The results of a new study provide a potential mechanism for these effects, suggesting that CrPic may play an important role in food intake regulation.
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AHCC Increases Survival of Mice following Infection |
October 9, 2008 |
AHCC or Active Hexose Correlated Compound is a unique extract from several different species of Basidiomycetes mushrooms. It has been shown in a number of studies to have antioxidant properties and has immune system boosting effects in both rodents and humans. AHCC has also been demonstrated to be beneficial in the treatment of cancer. A recent review examining the effects of AHCC supplementation on mice exposed to a variety of infectious diseases and illnesses highlights the impressive potential of AHCC.
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Probiotics Help Improve the Symptoms of Irritable Bowel Syndrome |
October 8, 2008 |
Irritable bowel syndrome (IBS) is a condition that is characterized by symptoms such as abdominal pain, diarrhea, and constipation, and that affects approximately 35 million Americans. The causes of this disorder are not well understood, although it is believed to be caused by a number of different factors. Recent findings have suggested that one factor is an impaired function of the intestinal mucosal barrier, which leads to an increase in intestinal permeability. Intestinal permeability, accompanied by inflammation has been found to be increased in patients with diarrhea-predominant irritable bowel syndrome (D-IBS). One possible solution for this problem is the use of probiotics, or bacteria that are healthy for the gastrointestinal system. Probiotics can interact with the host gut lining to decrease inflammation and to preserve the function of the barrier. Lactic acid bacteria have been found to be particularly promising in this area.
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Probiotics may reduce eczema in children by 50% |
October 3, 2008 |
A detailed clinical study recently completed in New Zealand has answered at least some of the questions surrounding the role of probiotics and their purported ability to prevent allergic diseases. It was answered with great emphasis placed on the particular strains of probiotics as well as the highly sensitive nature of the test subjects – in this case newborns born to parents with a family medical history that defines them as “high risks” for developing eczema.
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Olive Leaf Extract Helps to Reduce Blood Pressure |
October 2, 2008 |
The benefits of olive leaf have long been recognized by Mediterranean people. Olive leaf extract is especially well known for its antioxidant, antiviral and antibacterial properties. Recent evidence has also suggested that supplementation with olive leaf extract can have antihypertensive effects. A new study investigating the ability of olive leaf extract to lower blood pressure in pairs of identical twins provides further support for this.
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Indian Gooseberry Can Protect Against Second-hand Smoke |
September 30, 2008 |
In the emerging nutrition category that has informally come to be called “superfruits”, Indian Gooseberry, otherwise known as Phyllanthus emblica, Emblica Officinalis or simply amla, is slowly but surely emerging from its roots in Ayurveda to establish itself with modern science as a force to be reckoned with in today’s world of preventative medicine.
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Atherosclerosis Prevention: Another Reason to Take Vitamin K2 |
September 29, 2008 |
Coagulation…Bone health….prostate cancer prevention…the list of benefits for Vitamin K in general (and Vitamin K2 in particular) continues to grow. The latest condition to be added to the list appears to be atherosclerosis, characterized in part by a process known as calcification (the build-up of calcium deposits in the arteries).
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Probiotic Bacteria may help Modulate Seasonal Allergies |
September 16, 2008 |
A recent study published in Clinical and Experimental Allergy provides new evidence to suggest that probiotics may also have potential for the prevention of seasonal allergic rhinitis (hay fever). With as many as 40 million Americans suffering from seasonal allergy symptoms, this research could prove extremely beneficial. The study examined the effects of one specific strain of bacteria – Lactobacillus casei. This species of bacteria has been widely studied for its health-promoting properties and is commonly included in probiotic supplements. 20 individuals suffering from seasonal allergic rhinitis were given either an L. casei containing supplement or a placebo for 5 months. Over the five month period, supplementation with L. casei bacteria was found to have systemic effects on anti-body responses, modulate cytokine production and modulate non-specific immunity.
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Maternal DHA Levels are Associated with Birth Weight |
September 15, 2008 |
A recent study observed the associations between birth weight, birth length or head circumference and the maternal plasma levels of DHA, arachidonic acid (AA, an essential omega-6 fatty acid) and arachidonic acid’s precursor, DGLA. 782 mother-infant pairs had their plasma levels assessed during early, middle and late pregnancy and at delivery. The study found that there were significant positive associations between maternal DHA levels and birth weight and head circumference. This was particularly true for DHA levels early in pregnancy, and remained significant even after adjusting for other factors such as maternal age, height, smoking and drinking during pregnancy, gestational age and infant sex. On the other hand, AA and DGLA contents in late pregnancy were negatively associated with birth weight. The study concluded that DHA levels early in pregnancy have a role in fetal growth-programming while AA works to limit fetal growth.
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Link Between Cognitive Impairment and B-Vitamin Deficiency Strengthened by Study |
September 10, 2008 |
There has always been an association between healthy cognitive function and an optimal intake of B-complex vitamins. The latest research now seems to have focused on the mechanism(s) by which cognitive function is compromised by insufficient B-vitamin consumption. That focus is now largely centered around homocysteine levels, as these rise in the absence of adequate B-vitamin nutritional support. Elevated homocysteine levels play a role in a literal plethora of health issues – including age-related cognitive decline, a plethora that may now include reducing the length and density of capillaries in the brain as a predisposition to that decline.
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More Heart Health Benefits of Omega-3 Fatty Acids: Helping Patients with Chronic Heart Failure |
September 8, 2008 |
Omega-3 fatty acids are well known for their beneficial effects on heart health, and recently they have been in the news again for just this reason. A recent study by a group of Italian researchers has shown that daily supplementation with omega-3 polyunsaturated fatty acids (DHA and EPA) may reduce mortality and the frequency of hospital admission in patients with heart failure. While the effectiveness of Omega-3’s in preventing and treating cardiac problems has been demonstrated before, this new study is the first to assess the beneficial effects of omega-3 supplementation in a large population. |
Vitamin D May Protect Against Multiple Sclerosis (MS) |
September 3, 2008 |
A recent review of the potential link between vitamin D levels and MS points out that the incidence of MS is correlated with geographic area, with the disease being far more prevalent at higher latitudes where there is less exposure to sunlight. Furthermore, sufficient vitamin D intake has been linked with a lower prevalence of MS. There is evidence to suggest that maintaining healthy vitamin D levels is especially important at a young age. The correlation between the onset of MS later in life and blood vitamin D levels was especially strong for blood levels measured before the age of 20. Furthermore, immigrants who move before the age 15 have been shown to take on the MS risk associated with their new country. |
Cardiovascular Benefits from Omega-3 Fatty Acids |
September 2, 2008 |
A recent study examined the associations between n-3 fatty acids and atherosclerosis in Japanese versus white populations in the United States. 926 Japanese, white, and Japanese-American men between the ages of 40-49 years were assessed for their carotid artery thickness, coronary artery calcification, and levels of serum fatty acids, as well as their intake of marine-derived n-3 fatty acids. Japanese men had the lowest levels of atherosclerosis and 2-fold higher levels of n-3 fatty acids than the other two populations. These men showed significant inverse associations between omega-3 levels and the prevalence of thickened carotid arteries, which remained significant after adjusting for other cardiovascular risk factors. |
Omega-3 and Healthy Eyes: More Proof |
August 30, 2008 |
The link between healthy eyesight and an adequate intake of omega-3 essential fatty acids has long been a source of speculation within the scientific and preventative health communities. Indeed, the former has only recently begun to publish the results of extensive studies establishing such a link, with one meta-analysis from Australia stating that a high intake of omega-3 fatty acids from fish and other sources can reduce the risk of AMD (Advanced Macular Degeneration) by up to 38 % (source: Archives of Ophthalmology, June 2008, Vol. 126, pp. 826-833). |
Curcumin has Potential in the Treatment of Pancreatic Cancer |
August 28, 2008 |
Pancreatic cancer is one of the most lethal types of cancers and currently approved treatments for it prove beneficial in less than 10% of patients. For this reason, finding alternative strategies for treating this form of cancer is very important. Previous studies have shown that curcumin is able to inhibit a certain transcription factor, NF-KB, which is active in patients with pancreatic cancer. This transcription factor plays a role in tumor growth, invasion, angiogenesis and metastasis. However, curcumin has poor bioavailability, and its ability to fight cancer in humans remains to be determined. A recent study examined whether oral doses of 8g of curcumin per day, for 8 weeks, would have any effect on pancreatic tumours in 21 individuals. The results, although preliminary, are promising. The 8g per day dose was not found to have any toxic effects, and produced detectable (although low) levels of curcumin in the blood. Furthermore, two of the patients examined showed a positive response to the treatment. |
Low Vitamin D Levels Associated with Increased Hip Fracture Risk |
August 27, 2008 |
The importance of maintaining healthy levels of vitamin D has been demonstrated again and again by the results of scientific studies. Low levels of vitamin D have been linked to a growing number of health problems including heart disease, cancer, stroke, chronic pain, and even all-cause mortality. Vitamin D is particularly important in its role as a regulator of calcium levels and in the maintenance of healthy bones. Low vitamin D levels have, in the past, been linked to increased fracture risk. A recent study adds to the body of evidence in this area, showing that low blood levels of vitamin D are associated with an increased incidence of hip fractures in post menopausal women. |
Sulforaphane May Reduce the Risk of Vascular Disease in Diabetics |
August 21, 2008 |
A recent study published in the journal Diabetes has reported that Sulforaphane is able to activate an important transcription factor called NF-E2-related-factor-2 (nrf2) which seems to reverse many of the damaging effects of high blood sugar levels on vascular epithelial cells. Nrf2 activates a number of genes that produce protective enzymes that combat reactive oxygen species and oxidative stress, and reverse the dysfunction of these cells. |
Low Levels of Vitamin D May be Associated with Chronic Pain in Women |
August 19, 2008 |
New evidence suggests that low levels of vitamin D may be related to chronic pain in women. A recent study examined pain scores and blood levels of 25-hydroxyvitamin D (25[OH]D – a non-active storage form of vitamin D) among nearly 7000, 45 year old men and women from England, Scotland and Wales. The results indicated that low levels of vitamin D are associated with an increased incidence of chronic pain in women, but curiously, not in men. On average 14.4% of women with blood levels of 25[OH]D less than 25nmol/L experienced this type of pain, compared to only 8.2% of women with levels of 75-99nmol/L. However, men with 25[OH]D levels less than 25nmol/L did not suffer from an increased occurrence in chronic pain. |
The Role of Potassium in the Treatment and Prevention of High Blood Pressure |
August 12, 2008 |
A recent review of the roles of various minerals in the treatment of hypertension has revealed that a diet high in potassium may be able to significantly reduce blood pressure. Potassium is a mineral that is required by the body for the maintenance of normal kidney function and for muscle contraction. Observations of lower incidences of hypertension and heart disease among isolated populations and in vegetarians has led to speculation that this may be related to higher levels of potassium in these types of diets. On average, individuals living in isolated populations consume much less sodium and more potassium than individuals living in industrialized societies. This difference in diet is associated with a far lower incidence of hypertension, with only 1% of the population being affected, in comparison to nearly 1 in 3 people in industrialized societies. |
Not Just For Your Bones: New Japanese Study Reveals Calcium Can Reduce the Risk of Stroke By 30% |
August 9, 2008 |
While calcium is well-known as being essential to bone health, its value with respect to cardiovascular health has only recently been hypothesized. That hypothesis was put to the test in a very large cohort study conducted in Japan, lasting from 1990 to 2003 and involving 41 526 Japanese men and women aged 40 to 59 years without a history of cardiovascular disease or cancer. |
Boswellic Acids Help Relieve Symptoms of Osteoarthritis |
August 8, 2008 |
A recent study published in “Arthritis Research & Therapy” has provided further evidence of the positive effects of Boswellia serrata extracts on the symptoms of osteoarthritis. The study included 70 patients suffering from osteoarthritis of the knee. These patients received either 100mg or 250mg of boswellic acid containing extract, or a placebo, daily for 90 days. Patients were evaluated for pain, physical function and the presence of a cartilage degrading enzyme (metalloproteinase) in the joint fluid at day 0, 7, 30, 60 and 90. Patients receiving either dose of boswellic acids demonstrated significant improvements in both pain and functional ability of the knee joint. Even more impressive is that patients receiving the 250mg dose showed these improvements as early as 7 days following the start of treatment and required other pain medication 72% less often than patients taking placebos. |
Vitamin C Reduces the Risk of Type 2 Diabetes |
August 5, 2008 |
A study examining the onset of type 2 diabetes across a sample of 21 831 individuals that were part of the EPIC-Norfolk (European Prospective Investigation of Cancer – Norfolk) study has correlated plasma vitamin C levels to the rick of developing type 2 diabetes. Plasma vitamin C levels of each individual were determined at the beginning of the study and assessments of fruit and vegetable intake were performed. Over a twelve year follow-up period 735 new cases of type 2 diabetes were diagnosed. Mean plasma vitamin C levels were lower in individuals with diabetes than those without, and higher plasma vitamin C levels were strongly linked to a decrease in the risk of developing diabetes. This was true even when other factors such as sex, family history of diabetes, alcohol intake, physical activity, body mass index, smoking status, educational level and social class were taken into account. Greater consumption of fruits and vegetables was also linked to a decreased risk of diabetes, although to a lesser extent. |
New Study shows that Gamma-Tocotrienol is the most Cardioprotective Tocotrienol Within the Vitamin E Spectrum |
August 4, 2008 |
In a recent study published in the AJP-Heart and Circulatory Physiology, 2008, researchers at the University of Connecticut School of Medicine, used various isomers of tocotrienols, to study the effects and mechanism of tocotrienols’cardioprotective function especially on their ability to improve post-ischemic ventricular function and reduce myocardial infarct size in rats. The results showed that all forms of tocotrienols used (the palm tocotrienol complex and individual tocotrienol isomers) were able to provide significant cardioprotection. However, gamma-tocotrienol was the most cardioprotective of all the isomers. This is an interesting finding with far reaching consequences as the gamma-tocotrienol form (and gamma-tocopherol) is the most abundantly found in our diet. |
Vitamin K Good for Young Bones Too |
July 28, 2008 |
It has been well-established that Vitamin K is helpful for bone health, particularly in cases of osteopenia and osteoarthritis, conditions that are most common among post-menopausal women. However, a recent study out of Holland suggests that maintaining adequate levels of Vitamin K during adolescence may be just as important for the long-term (and even short-term) maintenance of bone health. |
Vitamins C and E Block Memory Impairment Associated with a High-Fat Meal in Diabetes Patients |
July 24, 2008 |
A recent study explored the issue of postprandial oxidative stress on meal-induced memory deficits, and the role of antioxidants. 16 adults over 50 years of age with type 2 diabetes mellitus were fed a high-fat meal (which produces the greatest increase in oxidative stress and proinflammatory molecules) with or without vitamins C and E, or water without a meal. After the meal ingestion, participants were given a variety of cognitive tests. It was found that participants who took the vitamins with their meal performed these tests at the same level as the participants who took only water, while those who consumed the meal without the vitamins had a lower performance. |
Omega-3 Intake during Pregnancy Is Linked to a Reduced Risk of Asthma in Children |
July 22, 2008 |
A recent randomized, double-blind study published in the American Journal of Clinical Nutrition observed the effects of maternal intake of omega-3s during pregnancy on the risk of asthma in their offspring. 533 women with normal pregnancies were given fish oil capsules, olive oil capsules or nothing to be taken from around 30 weeks of gestation until delivery. The groups were followed-up after 16 years to assess the number of cases of asthma in the children from each group. The study found a 63% decreased hazard rate of asthma in the fish oil group compared with the olive oil group. |
More Green Tea Benefits for Heart Health |
July 9, 2008 |
Many studies have found an association between tea consumption and a reduced risk of cardiovascular disease. The cells that line blood vessels are endothelial cells, and coronary endothelial function is essential for the function of the cardiovascular system. Endothelial dysfunction is a major event in the progression of atherosclerosis, where plaque builds up in blood vessels. A recent randomized, sham procedure-controlled, crossover study observed the effects of green tea and caffeine on flow-mediated dilatation (FMD) of the brachial artery, which is related to coronary endothelial function and is an independent predictor of cardiovascular risk. The study found that while caffeine and water had no significant effects, green tea consumption significantly increased flow-mediated dilatation of the brachial artery. |
Artichoke Leaf Extract Helps Lower Cholesterol Levels |
July 4, 2008 |
A recent randomized, double-blind, placebo-controlled parallel trial observed the effects of artichoke leaf extracts on plasma lipid levels of adults with mild to moderate hypercholesterolemia. 75 participants (who were otherwise healthy) were given either the extract or a placebo for 12 weeks. At the end of the study, participants in the test group had a 4.2% decrease in plasma total cholesterol, compared to a 1.9% increase in the control group. This decrease, although modest, was statistically significant. Previous studies have found even higher (18%) decreases in cholesterol levels. It appears that artichoke leaf is a helpful aid in controlling cholesterol levels. |
Low Vitamin D is Associated with All-Cause Mortality |
July 1, 2008 |
A recent study observed the associations between 25-hydroxyvitamin D (25-OH D, the plasma form of the vitamin) and 1,25-dihydroxyvitamin D (the active form) with cardiovascular and all-cause mortality. 3258 patients who were scheduled for coronary angiography had their levels of vitamin D assessed, and were followed-up for a period of almost 8 years. The results of the study found that patients with the lowest levels of 25-OH D were most at risk for all-cause mortality and cardiovascular mortality compared to patients with the highest levels. Similar results were found with levels of 1, 25-dihydroxyvitamin D. Vitamin D status was also significantly associated with markers of inflammation and oxidative damage. These results were independent of other potential factors such as coronary artery disease, physical activity level, and co-morbidities. |
Increased Omega-3 Intake Can Help Control Appetite Among The Obese |
June 26, 2008 |
With over half of all Europeans and nearly two-thirds of Americans now officially classified as overweight, reactions to this disease of privilege have been generated from the preventative health communities to public health authorities down to the food industry itself. Some of the proposed solutions have been based on increasing the nutrient density of food, thereby increasing satiety and subsequently decreasing appetite and caloric intake. |
Multivitamin Supplements Improve the Cognitive Performance of Children |
June 24, 2008 |
A recent randomized, double-blind, placebo-controlled parallel group study tested the effects of a multivitamin/mineral supplement on cognitive performance and mood in children. 75 children between the ages of 8 and 14 were given either a supplement or placebo for 12 weeks, and were tested on a variety of laboratory trials. The supplement contained nutrients including vitamins A, B, C, D3 and E as well as folic acid, biotin, copper, calcium, zinc, magnesium, lysine, and B-carotene. Although the multivitamins had no apparent effect on mood, there was a consistent pattern of improvement in laboratory tests that observed accuracy of performance, as well as an improved reaction time. One of the tests that supplemented children performed better on was designed to assess attention in the presence of distracting information. The study concluded that the supplement had beneficial effects on selective attention. |
EPA May Help Inhibit the Development of Esophageal Adenocarcinoma |
June 20, 2008 |
A recent study published in the American Journal of Clinical Nutrition tested the effects of supplementation with the omega-3 fatty acid eicosapentaenoic acid (EPA) on biological endpoints in Barrett’s esophagus. 27 patients with the premalignant condition were randomly assigned to a control group or a group supplemented with EPA for 6 months. At the end of the study, there was a significant decline in concentrations of cyclooxygenase 2 (COX-2) in the supplemented group which was inversely related to the change in EPA concentrations. COX-2 is an enzyme that is responsible for the production of pro-inflammatory mediators. Overexpression of this enzyme has been shown to occur in both esophageal adenocarcinoma and Barrett’s esophagus, and can lead to a reduced rate of cell death of abnormal cells, increased invasiveness of cancerous cells, and increased development of blood vessels to feed the cancerous growth. |
Methyltetrahydrofolate is More Effective than Folic Acid |
June 16, 2008 |
A double-blind, placebo-controlled study recently published in the European Journal of Clinical Nutrition observed the effects of MTHF compared to folic acid or placebo on elevated homocysteine levels in liver transplant recipients. These patients generally have increased levels of homocysteine which, along with a high incidence of obesity, arterial hypertension, and diabetes mellitus put them at an increased risk for cardiovascular disease. 48 patients were given 1 mg MTHF/day, 1 mg folic acid/day, or placebo for 8 weeks. At the end of the supplementation period, there was a significant 37% decrease in total plasma levels of homocysteine in the MTHF group. This decrease was still present after 2 weeks of follow-up. |
Calls to Raise RDA for Vitamin D Might Become ‘Deafening’ Upon Release of Heart Attack Study |
June 12, 2008 |
The mainstream media has paid an unusual amount of attention to vitamin D in recent months. The latest study was conducted by Harvard University’s School of Public Health. It involved the analysis of the medical history of 454 men aged 40-75 with a history of myocardial infarctions - including fatal ones - as the aforementioned records also encompassed those belonging to subjects who were deceased. These records were then examined against 900 healthy ‘control’ male subjects of the same age group, and after factors such as lifestyle (smoking, alcohol consumption, etc.) and diet were taken into account, the Harvard researchers made a significant observation regarding vitamin D. They found that men with lower circulating levels of the vitamin were 109% more likely to suffer a heart attack than those whose circulating levels of vitamin D were sufficient. |
Vitamin C Reduces the Risk of Heart Disease |
June 11, 2008 |
A recent meta-analysis examined the effect of vitamin C supplementation on LDL (“bad” cholesterol), HDL (“good” cholesterol) and triglyceride concentrations in patients with high cholesterol levels. Overall, the meta-analysis found that vitamin C supplementation leads to a significant reduction in the levels of both LDL cholesterol and triglycerides. Based on previously determined risk assessments, the analysis suggested that vitamin C supplementation could potentially reduce the risk of coronary heart disease by 6-11%. |
Joint Health Added to Pomegranate’s Growing List of Benefits |
June 9, 2008 |
Pomegranate has become well known in the preventative health community for its antioxidant, anti-atherogenic, anti-carcinogenic, anti-inflammatory, and glutathione-enhancing capabilities. Lately however, pomegranate research has also begun to establish inroads into some surprising areas of health prevention and maintenance. These include such unexpected fields as obesity and more recently, joint health. |
DHA Helps Improve Atopic Eczema |
June 5, 2008 |
A randomized, double-blind, controlled study recently published in the British Journal of Dermatology (2008;158:786-792) studied the effect of DHA on patients with atopic eczema. 53 patients from 18 to 40 years of age were given high-dose DHA or placebo for 8 weeks, with a 12 week follow-up. At the end of the study, it was found that there was a significant clinical improvement of eczema in the DHA group, which was determined by a decreased SCORAD (severity scoring of atopic dermatitis) index. There was also a significant reduction in the synthesis of IgE by immune cells. |
Low Levels of EPA are Associated with the Severity of Depression in the Elderly |
June 2, 2008 |
A recent study from France observed the association between plasma levels of fatty acids and the severity of depressive symptoms. 1390 subjects with an average age of 75 years participated in the study. Researchers found that plasma levels of EPA were significantly lower in the individuals with depression than in control subjects. The association of EPA levels and severity of depression remained significant even after adjusting for other factors, such as sociodemographic characteristics and health factors. |
10-Fold Increase In Vitamin D Needed For Children; Say Experts |
May 30, 2008 |
The current Recommended Daily Allowances (RDA’s) for Vitamin D of 200 International Units (IU) need to be increased to 2,000 IU in order to achieve the serum levels of Vitamin D (in the form of the hormone 1,25 [OH]2D) that is considered optimal for adults. This is according to a new long-term study that examined both low (200 IU daily equivalent) and high (2,000 IU daily equivalent) Vitamin D supplementation on 340 children (168 female; 172 male) aged 10 to 17, over the course of one year. |
Lutein and DHA May Help Prevent Age Related Macular Degeneration |
May 27, 2008 |
A new study from the American Journal of Clinical Nutrition tested the effects of lutein and DHA on macular pigment optical density (MPOD). 49 women between the ages of 60 and 80 were randomly assigned to be given DHA, lutein, a combination of both, or a placebo for 4 months. At the end of the study, it was found that the spacial pattern of increases in MPOD varied depending on the supplement. Women given lutein had increased MPOD at each retinal locus and women given DHA had an increase in the most central locus. |
More Research Supporting Lignans As Protection Against Prostate Cancer |
May 22, 2008 |
Lignans are phytonutrients, beneficial chemical compounds found in plants – such as isoflavones – which exhibit a degree of hormone-like activity. It is this fact that has led to the study of lignans pertaining to breast cancer for women and prostate cancer for men, and a recent study has bolstered the research behind the latter. |
Curcumin’s Benefits May Extend to Diabetes |
May 14, 2008 |
Curcumin, a pigment derived from the spice turmeric, is well-known for its anti-inflammatory, anti-oxidant, cardio-protective and other health-enhancing benefits. According to a Joint US-South Korea study, the increasingly ubiquitous nature of curcumin’s benefits may now encompass insulin sensitivity, and thus may offer relief to diabetics. |
Higher Levels of Vitamin D May Reduce the Risk of Fatal Cancer |
May 13, 2008 |
A new study from Germany examined the prospective association between vitamin D levels and cancer mortality in patients who were routinely referred to coronary angiography. 3257 patients were compared, none of whom had known advanced cancer at the beginning of the study. The patients’ levels of 1,25(OH)2D (active vitamin D) and 25(OH)D (a marker of vitamin D status) were measured. Follow up was done to determine incidences of cancer mortality. The results of the study showed that low concentrations of serum 25(OH)D were associated with an increased risk of fatal cancer. The risk of cancer mortality was reduced by 34% for every increase of 25 nmol/L in blood levels of 25(OH)D. |
EPA Shown to be as Effective as an Antidepressant Drug |
May 06, 2008 |
A new study published in the Australian and New Zealand Journal of Psychiatry compared the effects of EPA in depression to those of the antidepressant drug fluoxetine. 48 patients who were diagnosed with major depressive disorder were given either 1000 mg EPA or 20 mg fluoxetine or both for 8 weeks. At the end of the study, it appeared that EPA was at least as effective in controlling symptoms of depression as the drug, and both together were especially effective. There was a response rate of 50% to fluoxetine, 56% to EPA and 81% to the combination. |
Soluble Fibre for Weight Loss |
April 30, 2008 |
Consuming soluble fiber such as ß-glucan, pectin, and glucomannan, which is found in such foods as oats and barley, is well-known as a proven and effective way to reduce unhealthy levels of cholesterol. However, soluble fiber is now also being re-appreciated for another of its fundamental benefits which is more important now than ever – weight loss. |
DHA Improves Heart Rate Variability |
April 28, 2008 |
In a recent randomized, double-blind, parallel comparison study, 65 sedentary, overweight individuals with risk factors for cardiovascular disease were given fish oil with a 4:1 mix of DHA and EPA or a placebo each day for 12 weeks. At the end of the study, it was found that the fish oil supplementation significantly improved heart rate variability compared to the placebo group, as well as reducing heart rate during rest and light exercise. |
Vitamin K2 May Reduce The Risk of Prostate Cancer By 35% |
April 24, 2008 |
Although Vitamin K does not resonate with the same familiarity as Vitamins E or C, it is slowly but steadily gaining recognition from scientific and preventive health communities towards an increasingly essential status. The science behind Vitamin K as a blood coagulant is universally well established, and has also become increasingly fundamental in the area of bone health –albeit usually at higher dosages. Vitamin K has also begun to make its presence felt in the field of skin health and, according to a recent study, may also be a factor in the prevention of prostate cancer. |
Diabetes and Vitamin D: An Early Natural Defense |
April 21, 2008 |
Bone health has always been the primary health condition associated with Vitamin D, and for good reason. However, it is almost becoming the norm for scientists to examine nutritional pillars like Vitamin D and find within them a range of health benefits hitherto unknown and/or unappreciated. In the case of Vitamin D, a pair of scientists from the Central Manchester and Manchester Children's University Hospitals in the U.K. have recently completed a meta-analysis of five observational studies encompassing 6,455 human subjects in the study of supplemental Vitamin D. Of particular interest was the fact that these subjects were all infants under the age of one year, and that the effect of Vitamin D supplementation was measured not in terms of bone health, but rather in the prevention of type-1 diabetes. |
CoQ10 decreases exercise-induced fatigue |
April 17, 2008 |
A recent double-blind, placebo-controlled, three crossover design study tested the effects of CoQ10 on physical fatigue. 17 healthy volunteers were randomized to receive 100 mg or 300 mg of CoQ10 /day or a placebo for 8 days. At the end of the week, they performed a workload trial on a bicycle ergometer to induce fatigue. To determine physical performance, they performed non-workload trials at maximum velocity for 10 seconds at 30 minutes and 210 minutes of the fatigue-inducing trial. The study found that the decrease in physical performance due to physical fatigue was inhibited in the higher dose CoQ10 group compared to the placebo. Also, CoQ10 alleviated the sensation of subjective fatigue after the physical task and recovery period compared to the placebo group. |
Lutein and Zeaxanthin Can Cut the Risk of Blindness from AMD by Nearly Two-Thirds |
April 14, 2008 |
In Australia, AMD is the cause of blindness for over 80% of people aged at least 50 who fit the legal definition of blindness in that country (defined as being able to see at 6 metres what people with ‘normal’ vision can see at 60 metres). Scientists there have just completed a large, population-based cohort study, with corresponding results revealing that higher intakes of the carotenoids lutein and zeaxanthin can reduce the risk of AMD by 65%. |
Growing Evidence for Curcumin as Protection Against Heart Failure |
April 10, 2008 |
There are few natural health supplements whose reputation for effectiveness matches that of curcumin, the principle polyphenol found in the Indian spice turmeric. It has even been dubbed “curecumin” by certain scientists and all but revered as a panacea by many in the preventative health community. It is one of the most effective anti-inflammatories in the natural world, and its list of heath-enhancing properties is growing as scientists probe continuously deeper into its pharmacological mechanism(s) of action.
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Probiotics May Reduce the Risk of Antibiotic Associated Diarrhea |
April 4, 2008 |
Probiotics are bacteria normally found inside the human body that are inextricably linked with the body’s biological functions, including regulating the immune system and helping with digestion. Several strains of bacteria that are found in the gastrointestinal tract have been found to exert beneficial effects as supplements.
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Lutein and Zeaxanthin Improve Vision under Glaring Light Conditions |
April 2, 2008 |
Lutein and zeaxanthin are macular pigments that many studies have linked to improved vision. Besides being potent antioxidants, they are found in the retina in an optimal position for screening vulnerable photoreceptor cells and have been found to absorb harmful blue light. While lutein and zeaxanthin have been often studied with regard to age-related macular degeneration in the elderly, their filtering abilities may benefit vision in younger people as well.
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Low Folate May be a Risk Factor for Tumour Progression |
March 28, 2008 |
Hepatocellular carcinoma (HCC) is a form of cancer that is increasing in incidence worldwide and that is currently the 3rd most frequent cause of cancer-related death in men. Studies have indicated that low levels of folate are associated with an increased risk of liver damage and HCC.
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Higher levels of vitamin D may help with weight loss |
March 26, 2008 |
Vitamin D is an essential nutrient that is involved in regulating calcium and phosphate and has well established roles in bone health. It is also associated with lower risks of diabetes, autoimmune disorders, cardiovascular disease, and certain cancers. However, a new study suggests that it may also be helpful for people trying to lose weight.
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Low levels of magnesium may increase the risk of gallstones |
March 20, 2008 |
Magnesium is a mineral that is found in abundance in cells and that has essential roles in many biological functions. Unfortunately, magnesium intakes have decreased over the years and many people do not get enough of this important nutrient. While, magnesium’s importance in cardiovascular health is fairly well known, it has other roles as well. Current research suggests that a shortage of magnesium may contribute to gallstone formation.
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Probiotics Help Elite Athletes Avoid Illness |
March 14, 2008 |
An irony among elite endurance athletes is that due to the fact that they are 'pushing the envelope' of human endurance in order to constantly remain competitive, they make themselves more susceptible to upper respiratory tract infections due to exercise-induced immunosuppression. Recent studies however, point to probiotics as a viable method of reducing both the frequency and impact of these ironies.
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Improved Vitamin K Status Benefits Children's Bones |
March 06, 2008 |
A new study published in the British Journal of Nutrition set out to determine whether vitamin K status is related to bone mineral content in youth. 281 healthy children around 11 years of age had their bone mineral content and vitamin K status determined at baseline, and again 2 years later. The study found a relative shortage of vitamin K in participants’ bones, likely resulting from an imbalance between dietary vitamin K intake and the body’s requirement for the vitamin. Vitamin K status was also related to pubertal stage, which suggests that vitamin K status is impaired in advanced stages of puberty when growth rate is at its highest. Vitamin K status was positively correlated with markers of bone metabolism. Higher vitamin K at baseline was associated with higher bone mass, and an improvement in vitamin K status over the 2 year period was associated with a more pronounced increase in total body BMC.
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High folate intake may reduce the risk of stroke in smokers |
February 29, 2008 |
Elevated levels of homocysteine are known to increase the risk of ischemic stroke, and equally established is the role of folate in reducing blood levels of homocysteine. In a new study from the American Journal of Epidemiology (Larsson et al. Published online ahead of print Feb 12, 2008), researchers observed the association of high dietary folate, vitamin B6 and vitamin B12 with the risk of ischemic stroke. In this randomized, double-blind, placebo-controlled prevention trial, 26556 male Finnish smokers aged 50-69 years had their dietary intakes assessed at baseline and were followed up for an average of 13.6 years. At the end of the study, it was found that dietary folate intake was significantly inversely associated with the risk of cerebral infarction, an ischemic condition that leads to brain tissue death.
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Effectiveness of Citicoline Supplementation Demonstrated in Detail by New Technology |
February 26, 2008 |
Citicoline belongs to a category of supplements whose potency and benefits far exceed any degree of public awareness they have been able to generate, even among medical practitioners and preventative health professionals alike. This is an ironic phenomenon, curious but by no means rare and certainly not limited to the world of natural health. However, a new study utilizing cutting-edge medical technology might create some new converts to the potential of citicoline supplementation while further cementing the belief of the faithful.
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Coenzyme Q10 reduces exercise-induced muscular injury in athletes |
February 21, 2008 |
A new study published in the British Journal of Nutrition (Kon et al. 2008; published online ahead of print) examined the effects of CoQ10 on exercise-induced muscular injury in athletes. The participants in the study were 18 male students who were taking part in a 6 day kendo training camp. Kendo is a traditional Japanese sport that involves highly intense exercise, causing an increase in oxidative stress and cellular damage. The kendoists were randomly assigned in a double-blind manner to be given either placebo capsules, or 100 mg of CoQ10 three times a day. Blood samples were taken to measure creatine kinase activity and serum myoglobin concentrations, which are the most commonly used markers of skeletal muscle damage. The study found that both serum creatine kinase activity and serum myoglobin concentrations increased significantly during the trial period compared to initial levels. The percent changes of both markers were significantly lower in the CoQ10 group than in the placebo group, indicating that CoQ10 reduced exercise-induced muscular injury.
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Vitamin deficiency in morbidly obese patients |
February 15, 2008 |
Morbid obesity is a condition defined as a body mass index of over 40, or over 35 with weight related comorbidity. This condition affects an estimated 7% of adult women in the US and is associated with an impaired quality of life, increased risk of coronary heart disease, and shortened life expectancy. Individuals with this condition have greater dietary intakes than those who are nonobese, yet they can be at risk for deficiencies of essential nutrients. A new study published in the American Journal of Clinical Nutrition examined serum levels of various nutrients in 110 patients with morbid obesity, and in 58 healthy controls. Blood tests showed several differences in vitamin status of morbidly obese patients compared to healthy controls, with significant differences in 6 of the 9 vitamins tested. Both men and women who were morbidly obese had significantly lower levels of vitamin B6, vitamin C, 25-hydroxyvitamin D, and vitamin E than the healthy controls. 11-38% of patients had inadequate levels of these vitamins, with the most pronounced deficiencies in the most obese patients.
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Low levels of vitamin E are associated with decline in physical function |
February 8, 2008 |
A new study published in the Journal of the American Medical Association (2008;229(3):308-315) investigated the effects of a low serum concentration of micronutrients on physical decline in older men and women. 698 individuals 65 years or older participated in this longitudinal study. Participants underwent a medical exam and an assessment of their plasma micronutrient concentrations and physical function, and were followed up after 3 years to determine the incidence of physical decline (defined as a loss of at least one point in the Short Physical Performance Battery). Other than age, vitamin E status was identified as the strongest determinant of decline in physical function. An age of over 81 years was related to physical decline in 84% of participants, and low vitamin E status led to a decline in physical function in 61%. This association did not depend on the initial degree of physical performance. Researchers analyzed the results using 3 analytical approaches, and consistently found the same associations.
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Astaxanthin 800 times more potent than co-enzyme Q10 at quenching singlet oxygen free radicals |
February 6, 2008 |
Astaxanthin has exceptional antioxidant activity to combat singlet oxygen when compared to other antioxidants. In particular, astaxanthin can be used to defend against singlet oxygen damage for eye and skin health, which are especially susceptible to UV damage and aging effects. Singlet oxygen is an active oxygen species generated in human skin by exposure to ultraviolet radiation (UV) that causes skin damage and eye damage. In a recent study, astaxanthin extracted from Haematococcus microalgae powerfully quenched singlet oxygen. Results show that the quenching effect of astaxanthin is 800 times greater than coenzyme Q10. Astaxanthin was also about 75 times greater than alpha lipoic acid, about 550 times greater than green tea catechins and about 6000 times greater than vitamin C.
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Lutein and zeaxanthin decrease the risk of developing cataracts |
February 1, 2008 |
Cataracts are a common vision disorder defined as a clouding of the crystalline lens of the eye. Age-related cataracts affect over 50% of people 65-74 years old, and the risk increases with increasing age. A new study published in the Archives of Ophthalmology (2008;136(1):102-109) examined the association between carotenoid and vitamin E intake and the risk of cataracts in women. Researchers obtained detailed information on antioxidant nutrient intake from 35 551 female health professionals who had no cataracts. The women were followed up for an average of 10 years to determine the incidence of cataract formation, which was defined as “an incident, age-related lens opacity responsible for a reduction in best-corrected visual acuity in the worse eye to 20/30 or worse based on self-report confirmed by medical record review”. At the end of follow-up, results indicated that higher dietary intakes of the carotenoids lutein and zeaxanthin, as well as vitamin E, were associated with a significantly lower risk of developing cataracts.
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B-Vitamin Benefits for Pregnancy: The Evidence Keeps on Growing |
January 29, 2008 |
It has long been established that folate is important for the prevention of neural tube defects in newborns, making it part of the standard pre-natal protocol. It has been speculated that folate is unlikely be the sole B-vitamin that warrants such prominence in prenatal nutrition, and new research out of Holland suggests that this may be closer to becoming fact.The Dutch scientists found a significant relationship between the combination of low maternal B12 levels and specific genotypes in both the mothers and their children, and the rate of congenital heart defects among those children.
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Probiotics decrease stress-induced gastrointestinal problems |
January 28, 2008 |
Probiotics are live microorganisms that, instead of making us sick, actually provide health benefits. A new study published in the journal Nutrition Research (2008;28:1-5) tested the effects of two probiotic strains, Lactobacillus acidophilus and Bifidobacterium longum, on symptoms of stress. Both strains are found in normal human intestinal microflora and are important for improving lactose tolerance, increasing intestinal smooth muscle contraction and helping bowel function. In this double-blind, placebo-controlled, randomized study, 64 healthy volunteers with symptoms of stress were given either a probiotic containing the two bacterial strains or a placebo for 3 weeks. At the end of the supplementation period, symptoms of stress-induced abdominal pain and nausea/vomiting were significantly improved. There was also a tendency for reduced gas production in the test group.
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Green tea reduces the risk of cardiovascular problems |
January 24, 2008 |
A recent study from the International Heart Journal (2007;48:725-732) observed the effects of catechin intake on lipids and oxidized low density lipoprotein (LDL) in the blood. In this randomized controlled study, 40 healthy adults were divided into either a catechin or control group. The catechin group received the equivalent of 6 or 7 cups of green tea for four weeks. Blood samples were taken at the beginning and end of the study, and the blood levels of total cholesterol, triglycerides, LDL cholesterol, HDL cholesterol and oxidized LDL were measured. At the end of the study, the catechin group had significantly lower levels of plasma oxidized LDL.
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Large study in Scotland reveals that increased intake of vitamin B6 may reduce the risk of colorectal cancer by 19 per cent |
January 18, 2008 |
Colorectal cancer has been the focus of many a clinical study, but few have matched the depth and breadth of the one recently completed by researchers from the University of Edinburgh, Western General Hospital (Edinburgh) and the University of Aberdeen, in Scotland. The study involved nearly 5,000 people in both control and study groups, with the latter consisting of hospital-based colorectal cancer patients. The results were summarized by lead author Evropi Theodoratu as: "Moderately strong inverse and dose-dependent associations in the whole sample were found between CRC (colorectal cancer) risk and the intake of dietary and total vitamin B6.” The researchers elaborated that according to a meta-analysis of published studies, higher intakes of vitamin B6 were associated with a 19% lower risk of colorectal cancer - further supporting their findings - which also demonstrated a particularly pronounced benefit on those subjects aged 55 or younger.
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Low levels of vitamin D are linked to cardiovascular disease |
January 16, 2008 |
A new study published in Circulation, a Journal of the American Heart Association found that vitamin D levels are linked to cardiovascular health. In this study, 1739 participants had serum samples taken and had their vascular risk factors assessed, and were followed-up for an average of 5 years. Results showed that the 5-year rate of cardiovascular disease was approximately twice as high in people with vitamin D deficiency as in those with higher levels of the vitamin. This association remained significant even after adjusting for cardiovascular risk factors. Furthermore, when participants were divided into categories based on their vitamin D status, there was a stepwise increase in the risk of cardiovascular disease across the categories. The highest rate of cardiovascular disease was found in participants with both hypertension and vitamin D deficiency.
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Higher levels of vitamin C are linked to a decreased risk of stroke |
January 10, 2008 |
Vitamin C is an important factor in the human body, and has been linked to a lower incidence of stroke. This link is strengthened by a recent population-based prospective study that was part of the European Prospective Investigation into Cancer (American Journal of Clinical Nutrition. 2008;87:64-69). In this study, 20649 people aged 40-79 years with no history of stroke had their levels of plasma vitamin C measured. There appeared to be an inverse, dose-response linear relation between the baseline concentration of plasma vitamin C and the risk of stroke. Participants in the top quartiles of baseline plasma vitamin C had a 42% lower risk of stroke than those in the bottom quartile.
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Lycopene inhibits disease progression in men at risk for prostate cancer |
January 3, 2008 |
Lycopene, an important member of the carotenoid family, has shown promise in helping to prevent prostate cancer. A new randomized, double-blind, controlled study in the Journal of Nutrition (2008;138:49-53) evaluated the chemopreventive effects of lycopene supplementation in men with benign prostate hyperplasia (BPH). Clinical examination of the prostate found only a slight, nonsignificant increase of 3-5% in prostate volume and weight in the lycopene group, compared to a 24-27% increase in the placebo group. After adjusting for body mass index and baseline levels, the enlargement of the prostate was still slower in the lycopene group. Disease symptoms, which were measured by the International Prostate Symptom Score questionnaire, were improved in both groups with a significantly greater effect in the lycopene group.
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High prenatal DHA levels positively influence motor function in childhood |
December 21, 2007 |
A new study published in the European Journal of Clinical Nutrition (Bakker et al. Dec. 19 2007;advance online publication) investigated the association between plasma levels of DHA in the umbilical cord at birth and motor function in childhood. 209 children who were born at term and had had umbilical blood samples taken were assessed at 7 years of age for motor function. The study found a significant positive relation between the umbilical plasma concentrations of DHA and the motor function test scores. These results indicate that prenatal DHA availability, which can be influenced by maternal intake of DHA, may have an effect on the quality of movement in later life.
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Pomegranate displays possible anti-obesity effects in addition to its anti-carcinogenic properties, study finds |
December 14, 2007 |
Pomegranate is a recent addition to the field of antioxidant research, having been studied by scientists for its anti-carcinogenic and cardiovascular benefits since only the earlier part of this decade. However, a recent study published by the International Journal of Obesity in London, England entitled “Evidence of anti-obesity effects of the pomegranate leaf extract in high-fat diet induced obese mice” (2007 Jun; 31[6]: 1023-9) revealed that pomegranate extract may also have biochemical mechanisms of action that can counter some of the conditions of obesity. These include pomegranate’s apparent ability to inhibit the pancreatic enzyme responsible for processing fat, as well as the even more impressive ability to suppress appetite, a function more attributable to central nervous system stimulants than antioxidants.
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Adequate zinc levels may protect the elderly from pneumonia |
December 12, 2007 |
Zinc is well-known to play an important role in immune function. A study published in the American Journal of Clinical Nutrition tested whether serum zinc concentrations in the elderly are associated with pneumonia. During a one year randomized and controlled trial, nursing home patients were given supplements of various nutrients. Researchers found that patients who had normal concentrations of zinc had a lower incidence and shorter duration of pneumonia, fewer new antibiotic prescriptions and fewer days of antibiotic use. Furthermore, normal baseline zinc levels were found to be associated with a 39% reduction in all-cause mortality.
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Multiple supplement users have better overall health |
November 28, 2007 |
A recent study published in Nutrition Journal concluded that people who use multiple supplements have better overall health. Supplement users had significantly higher nutrient concentrations and reduced biomarkers associated with disease risk. Such biomarkers decreased with increasing supplement use and included elevated serum homocysteine, triglycerides, ratio of total cholesterol to HDL-cholesterol, and concentrations of C-reactive protein, a predictor of future cardiovascular disease risk.
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Low vitamin B-12 levels increase the risk of cognitive decline |
November 20, 2007 |
A new study published in the Journal of Clinical Nutrition examined the association of vitamin B-12 with cognitive decline in a longitudinal cohort study of 10 years. Researchers found that low levels of vitamin B-12 biomarkers were significantly associated with a more rapid rate of cognitive decline. Furthermore, a doubling in the concentrations of the biologically active fraction of vitamin B-12 was associated with a 30% slower rate of cognitive decline.
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Multivitamin/Multimineral Supplements Help Obese Dieters Keep The Weight Off |
November 19, 2007 |
Micronutrients such as Vitamin B6, Calcium, Vitamin B12 and numerous others are involved in the synthesis and regulation of powerful hormones such as leptin, cortisol, and insulin, which have an overwhelming effect on appetite and metabolism. According to a recent study published in the British Journal of Nutrition, this means that someone trying to lose weight on a low-calorie diet that is rich in nutrients is more likely to enjoy long-term success than someone trying to lose weight on a low-calorie diet that is not rich in nutrients.
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Higher vitamin D concentrations reduce the risk of age-related disease |
November 16, 2007 |
A new study published in the American Journal of Clinical Nutrition has found that vitamin D is associated with longer leukocyte telomere length (LTL). Leukocyte telomeres shorten with every cell cycle, so LTL decreases with age and is a marker of age-related disease. This study, which looked at serum vitamin D concentrations in a group of women, found that vitamin D was positively associated with LTL independent of age and other covariates. Vitamin D supplement users had longer LTLs than nonusers.
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AOR’s Homocysteine + can reduce the risk of heart disease |
November 2, 2007 |
A new study from the University of East London tested the effects of AOR’s Homocysteine+ on blood levels of homocysteine. Healthy and active participants were supplemented with either Homocysteine+ or a control pill for six weeks in a randomized, double-blind trial. Homocysteine+ significantly reduced homocysteine levels in all participants who received supplements compared to the control group.
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Vitamin E may reduce the risk of thromboembolism in women |
October 30, 2007 |
The Women’s Health Study tested the effects of vitamin E supplementation for 10 years on the decreased risk of cardiovascular disease or cancer. The trial was randomized and controlled and none of the women involved had the diseases at entry. It was found that vitamin E was associated with a significant reduction of 21% in the risk of venous thromboembolism (VTE), a 27% reduction in the risk of unprovoked VTE and a 28% reduction in the risk of pulmonary embolism. It was also found that in women with a prior history or with a genetic predisposition to VTE, vitamin E supplementation reduced the risk by 40%-49%.
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Connection between low Omega-3 Fatty Acid intake and depression further strengthened |
October 26, 2007 |
In a recent article published in the prestigious Journal of Clinical Psychiatry (2007;V. 68:1056-1061), scientists in Taiwan published a review of no fewer than 10 clinical trails examining the effects of Omega-3 Polyunsaturated fatty acids (PUFAs) on patients with mood disorders. The overall number of patients involved in the studies totaled 329 and all of the trials were at least 4 weeks in duration. In their summation of these studies, the Taiwanese scientists determined that omega-3 PUFA supplementation imparted a ‘significant antidepressant effect’. They added that ‘omega-3 PUFAs significantly improved depression in patients with clearly defined depression or with bipolar disorder.’
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N-Acetyl-L-Cysteine (NAC) can help esophageal cancer patients endure surgery |
October 4, 2007 |
A recent Swiss study examined the effects of high-dose NAC supplementation on 22 patients suffering from cancer of the esophagus who were undergoing or were about to undergo surgery. This dreadful disease wreaks havoc on those it inflicts both directly and indirectly – the latter being characterized by a high rate of pulmonary complications. NAC is well known for raising glutathione levels, scavenging reactive oxygen species of free radicals, and inhibiting inflammatory cytokines associated with such pulmonary disorders. This led the Swiss scientists to theorize that it may alleviate the occurrence of pulmonary complications in esophageal cancer patients who were in the process of undergoing surgery – when they were the most vulnerable.
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Sulforaphane protects the blood-brain barrier |
September 19, 2007 |
Sulforaphane may be able to protect and boost the blood-brain barrier when it is damaged. The blood-brain barrier is essential for normal brain function. It is mostly made up of a layer of specialized cells called endothelial cells and the tight junctions between them. These junctions act as a sort of zipper to seal the area between the cells and control which substances can pass between them, protecting the brain from harmful chemicals in the blood. Brain injury can cause the death of endothelial cells and the breakdown of tight junctions, damaging the integrity of the blood brain barrier and leading to various injuries and diseases of the central nervous system.
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Vitamin D supplements lower the risk of mortality |
September 10, 2007 |
People who take vitamin D supplements may have a better chance of living longer. A new meta-analysis has found that participants in studies who were followed over 6-7 years while taking vitamin D supplements had a 7% lower risk of death than those who did not take supplements and consequently had lower blood levels of the vitamin.
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Fish oil improves the elasticity of blood vessels |
September 5, 2007 |
Fish oil has been linked to improvements in the elasticity of blood vessels. Studies have shown that fish oils have a number of health benefits, from reducing the risk of cardiovascular disease to joint health and good development during pregnancy. A new study has shown that fish oil supplementation leads to improvements in large arterial elasticity in overweight hypertensive patients. Decreases in large arterial elasticity have been linked to cardiovascular mortality in patients with hypertension.
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Lycopene protects against advanced prostate cancer |
September 4, 2007 |
New research suggests that lycopene may offer protection against advanced prostate cancer. An study published in the American Journal of Clinical Nutrition followed men from eight European countries for 6 years, testing for prostate cancer and taking blood samples to establish the plasma concentrations of various carotenoids, including lycopene.
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Older adults benefit from dietary supplements |
August 15, 2007 |
A recent study suggests that older adults benefit from taking dietary supplements. This population often suffers from chronic disease, decreased dietary intake and absorption problems. Therefore a substantial portion of older adults do not get enough vitamins in their diets. This nutritional shortfall can be compensated at least to some extent by dietary supplements.
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Lycopene Reduces Airway Inflammation in Asthmatics |
June 11, 2007 |
Australian researchers have just released the results of the latest clinical trial on the health benefits associated with lycopene. The researchers found that asthmatics whose diet was supplemented with lycopene had significant improvements in airway inflammation compared to the patient group receiving a dummy pill. Airway inflammation is the main cause of asthma and a significant contributing factor in several other disorders of the respiratory system.
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Epicatechin Improves Learning and Memory in Mice |
June 10, 2007 |
A new study published in the Journal of Neuroscience has shown that epicatechin, a flavanol derived from green tea leads to the formation of new blood vessels in the part of the brain essential for new memories and learning. New blood vessels support the development of new neurons and allow brain cells to communicate with each other more effectively. Consumption of epicatechin also upregulated genes associated with learning while downregulating genes associated with neurodegeneration.
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Inositol Reduces Colon Cancer In Mice Affected With Ulcerative Colitis |
October 19, 2006 |
The inflammatory process is mediated by the release of histamine, kinins and various other inflammatory mediators. Inflammation is a non-specific response to foreign invasion or tissue damage. The purpose of the inflammatory response is to remove debris, attack foreign invaders, remove cellular waste and encourage the healing process. Unfortunately, in chronic inflammation as seen in auto immune disorders, persisting inflammation leads to oxidative stress because of the overproduction of reactive oxygen and nitrogen species as well as the depletion of antioxidant molecules – this in turn increases the risk of cancer.
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