Vitamin C is an antioxidant that has been linked to a wide range of health benefits, including reduced cholesterol levels and a reduced risk of cardiovascular disease. A recent study has provided evidence that plasma vitamin C levels, as well as consumption of vitamin C containing fruits and vegetables, may also be important in the prevention of type 2 diabetes mellitus.
The study examined the onset of type 2 diabetes across a sample of 21 831 individuals that were part of the EPIC-Norfolk (European Prospective Investigation of Cancer – Norfolk) study. Plasma vitamin C levels of each individual were determined at the beginning of the study and assessments of fruit and vegetable intake were performed. Over a twelve year follow-up period 735 new cases of type 2 diabetes were diagnosed. Mean plasma vitamin C levels were lower in individuals with diabetes than those without, and higher plasma vitamin C levels were strongly linked to a decrease in the risk of developing diabetes. This was true even when other factors such as sex, family history of diabetes, alcohol intake, physical activity, body mass index, smoking status, educational level and social class were taken into account. Greater consumption of fruits and vegetables was also linked to a decreased risk of diabetes, although to a lesser extent.
The antioxidant properties of vitamin C may be the key to explaining this correlation between plasma vitamin C levels, fruit and vegetable consumption, and the risk of diabetes. Imbalances in antioxidant levels can lead to oxidative stress, a situation that can disrupt glucose metabolism. Oxidative stress is common in individuals with diabetes, and may also be promoted by obesity, which is one of the greatest risk factors for diabetes. Antioxidants, like vitamin C, can help prevent oxidative stress. Overall, the results of this study provide strong evidence of a beneficial effect of increased vitamin C intake on the prevention of type 2 diabetes.
Harding et al. Plasma Vitamin C level, Fruit and Vegetable Consumption, and the Risk of New-Onset Type 2 Diabetes Mellitus: The European Prospective Investigation of Cancer – Norfolk Prospective Study. Arch Intern Med. 2008; 168: 1493-1499
For more information see Tapioca C and C + Bioflavonoids
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