It’s Official: Coenzyme Q10 Improves Heart Failure Survival

It’s Official: Coenzyme Q10 Improves Heart Failure Survival

At the annual meeting of the Heart Failure Association of the European Society of Cardiology, Dr. Svend Aage Mortensen, a professor at the Copenhagen University Hospital reported a significant reduction in deaths among heart failure patients who were given coenzyme Q10 supplements over a two year period. This is the first study to actually show reduced mortality in heart failure patients, giving a tangible end-result of CoQ10’s benefits on the heart.  

The 420 patients included in the Q-SYBIO study were being treated for Class III or IV heart failure as classified according to the New York Heart Association. Study subjects were randomly designated to receive either a placebo or 100mg of CoQ10 three times a day for a two year period.

At the end of the trial, only 14% of the participants who were taking the CoQ10 and 25% of the placebo group experienced a first significant and adverse cardiovascular event which required resulted in either hospitalization as a result of heart failure, urgent heart transplantation, mechanical circulatory support, or in death. Additionally, the risk of death was twice as high in the placebo group as it was in the group that was receiving the CoQ10 supplements.

In some countries (but not North America), CoQ10 is part of the standard statin prescription protocol. Dr. Mortensen suggests that CoQ10 also be added to standard chronic heart failure prescription protocols, given the solid results of this study. Many heart medications actually block cellular processes rather than enhance heart function and may also have the risk of causing side effects. CoQ10 supplements have been demonstrated to be safe and effective. They are able to correct energy deficiencies in the heart and stop the vicious cycle of energy deprivation which leads to the condition of chronic heart failure. Circulating CoQ10 also helps to effectively prevent the oxidation of LDL. AOR’s Co-enzyme Q10 and Co-Q Plus offer the same dosage of CoQ10 as was used in the clinical trial.


SA Mortensen, A Kumar, P Dolliner et al. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure. European Journal of Heart Failure: 2013; 15 ( S1 ) S20