Amla

Amla

Amla

Ayurvedic support for the heart

  • A natural fruit extract providing nutrient support for the heart
  • Helps reduce cholesterol and regulate blood sugar levels
  • Anti-inflammatory and Antacid
  • Provides a high dose of active tannins for maximal benefit

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DISCUSSION: AMLA is an extract of Emblica officinalis, which has been shown in clinical studies to prevent lipid peroxidation.

NPN (what's this?)Product CodeSizePer CapsuleVegetarian
80023254AOR0429290 Vegi-Caps950 mgVegetarian
Supplement Facts
Serving Size: 1 Capsule
Amla extract (Emblica officinalis)950 mg
 
Non-medicinal ingredients: silicon dioxide. Capsule: hypromellose. 

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Adult Dosage: Take 1 capsule three times a day with/without food, or as directed by a qualified health care practitioner.

Cautions: None Known.

Pregnancy/Nursing: Do not use

Source:
Emblica officinalis

Main Indications:

  • Antioxidant
  • Antiviral (colds/flu)
  • Anti-inflammatory
  • Cardiovascular disease
  • Bones, skin, collagen
  • Anti-tumor

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Disclaimer

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

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Research

Background Info

Amla (Emblica officinalis), also known as Indian Gooseberry, is a deciduous tree native to the Indian subcontinent and is a staple in Ayurveda, the ancient medicinal system of healing and longevity in India. The fruits of the tree are used for the aforementioned ayurvedic applications, which include treatment for diarrhea, dysentery, infections, and ulcers. Amla’s most notable mention in the ancient ayurvedic texts, however, is as a rasayana anti-aging compound.

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Research

Not surprisingly, Amla’s reputation is supported by scientific studies confirming its health-enhancing properties in a number of fields.

Cholesterol and Lipoprotein Metabolism
A number of published, peer-reviewed studies have confirmed amla as an effective modulator of lipoprotein metabolism. Indeed, there is a strong correlation between lipoprotein dysfunction and the aging process. One Japanese study found that amla lowered total cholesterol levels by up to 26%, while simultaneously raising levels of PPARalpha (an enzyme that is known to regulate the transcription of genes involved in lipid and cholesterol metabolism) by 48% in aged laboratory rats. This is an impressive expression of synergy considering that elevated lipid levels and depressed PPARalpha levels have a strong correlation with the aging process. Numerous other animal studies were equally impressive, which further served to establish amla’s effectiveness in dealing with abnormal lipid levels and cholesterol. In one such study, amla reduced serum cholesterol and LDL levels by 82% and 90%, respectively. Studies with humans have also shown promising results, with one double-blind, peer-reviewed Indian study showing that amla supplementation significantly reduced total serum cholestrol levels in both normal and hypercholesterolaemic men after just 28 days. In another human study, amla increased HDL cholesterol by 25% while reducing LDL cholestrol by nearly 16% in addition to significantly reducing postprandial glycemia in the oral glucose tolerance test by more than 12%.

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Market Trends

Amla as a dietary supplement is not very common. The Ayurvedic herb amla is known to be a nutrient dense fruit. It is traditionally believed to promote longevity, and is commonly seen on the market in hair products to reduce hair loss and delay premature greying of hair.

AOR Advantage

AOR’s Amla provides a very high dose of this supplement according to traditional Ayurvedic formulations and contains 40% tannins according to clinical trials.

References

Damodaran M, Nair KR. A tannin from the Indian gooseberry (Phyllanthus emblica) with a protective action on ascorbic acid. Biochem J. 1936 Jun;30(6):1014-20. 

Khopde SM, Priyadarsini KI, Mohan H, Gawandi VB, Satav JG, Yakhmi JV, Banavaliker MM, Biyani MK and Mittal JP. Characterizing the antioxidant activity of amla (Phyllanthus emblica) extract. Current Science. 2001;81(2):185-190.

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Reviews

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Abstracts

Amla (Emblica officinalis Gaertn.) prevents dyslipidaemia and oxidative stress in the ageing process.
Br J Nutr. 2007 Jun;97(6):1187-95.
Yokozawa T, Kim HY, Kim HJ, Okubo T, Chu DC, Juneja LR.

Amla (Emblica officinalis Gaertn.) is widely used in Indian medicine for the treatment of various diseases. We have investigated the effects of amla on the lipid metabolism and protein expression involved in oxidative stress during the ageing process. SunAmla or ethyl acetate extract of amla, a polyphenol-rich fraction, was administered at a dose of 40 or 10 mg/kg body weight per d for 100 d to young rats aged 2 months and aged rats aged 10 months. The lipid levels, such as cholesterol and TAG, in serum and liver were markedly elevated in aged control rats, while they were significantly decreased by the administration of amla. The PPARalpha is known to regulate the transcription of genes involved in lipid and cholesterol metabolism. The PPARalpha protein level in liver was reduced in aged control rats. However, the oral administration of amla significantly increased the hepatic PPARalpha protein level. In addition, oral administration of amla significantly inhibited the serum and hepatic mitochondrial thiobarbituric acid-reactive substance levels in aged rats. Moreover, the elevated expression level of bax was significantly decreased after the oral administration of amla, while the level of bcl-2 led to a significant increase. Furthermore, the expressions of hepatic NF-kappaB, inducible NO synthase (iNOS), and cyclo-oxygenase-2 (COX-2) protein levels were also increased with ageing. However, amla extract reduced the iNOS and COX-2 expression levels by inhibiting NF-kappaB activation in aged rats. These results indicate that amla may prevent age-related hyperlipidaemia through attenuating oxidative stress in the ageing process.

 

Influence of amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats.
J Nutr Sci Vitaminol (Tokyo). 2005 Dec;51(6):413-8.
Kim HJ, Yokozawa T, Kim HY, Tohda C, Rao TP, Juneja LR.

The effects of amla on low-density lipoprotein (LDL) oxidation and cholesterol levels were investigated in vitro and in vivo using Cu(2+)-induced LDL oxidation and cholesterol-fed rats. SunAmla and ethyl acetate (EtOAc) extract of amla significantly inhibited thiobarbituric acid (TBA)-reactive substance level in the Cu(2+)-induced LDL oxidation and the effects were stronger than those of probucol. In addition, the administration of SunAmla (at a dose of 20 or 40 mg/kg body weight/d) or EtOAc extract of amla (at a dose of 10 or 20 mg/kg body weight/d) for 20 d to rats fed 1% cholesterol diet significantly reduced total, free and LDL-cholesterol levels in a dose-dependent manner, and EtOAc extract of amla exhibited more potent serum cholesterol-lowering effect than SunAmla in the same amount. Furthermore, the oxidized LDL level in serum was markedly elevated in cholesterol-fed control rats as compared with normal rats, while it was significantly decreased by the administration of SunAmla or EtOAc extract of amla. Moreover, the serum TBA-reactive substance level was also significantly decreased after oral administration of SunAmla or EtOAc extract of amla. These results suggest that amla may be effective for hypercholesterolemia and prevention of atherosclerosis.

 

Effect of the Indian gooseberry (amla) on serum cholesterol levels in men aged 35-55 years.
Eur J Clin Nutr. 1988 Nov;42(11):939-44.
Jacob A, Pandey M, Kapoor S, Saroja R.

The effect on total serum cholesterol and its lipoprotein fractions of supplementation of the diet with amla (Emblica officinalis, Gaertn., the Indian gooseberry) was studied in normal and hypercholesterolaemic men aged 35-55 years. The supplement was given for a period of 28 d in the raw form. Both normal and hypercholesterolaemic subjects showed a decrease in cholesterol levels. Two weeks after withdrawing the supplement, the total serum cholesterol levels of the hypercholesterolaemic subjects rose significantly almost to initial levels.