Magnesium + Taurine

Magnesium + Taurine
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Magnesium + Taurine

  • Helps maintain healthy blood pressure
  • Stabilizes heart rate
  • Prevents over-excitability of the central nervous system
  • Antioxidant
Magnesium + Taurine, 1.0 out of 5 based on 2 ratings

DISCUSSION: Magnesium + Taurine helps the body metabolize carbohydrates, protein and fat, supports connective tissue formation, helps in the development and maintenance of bones and teeth, and helps maintain proper muscle function.

NPN (what's this?)Product CodeSizePer CapsuleVegetarian
80033916 AOR04324180 Vegi-Caps365 mgVegetarian
Supplement Facts
Serving Size: 1 Capsule
Magnesium (citrate)65 mg
Taurine300 mg
Non-medicinal ingredients: Capsule: hypromellose.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Adult Dosage: Take 1 capsule one to five times daily with/without food, or as directed by a qualified health care practitioner.

Cautions: None known

Pregnancy/Nursing: Consult a qualified health care practitioner

Source:
Pharmaceutical synthesis

Main Indications:

  •  Cardiovascular support
  •  Neurological disorders

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Disclaimer

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

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Research

Background Information

Background Information
Magnesium Taurate is a combination of the mineral magnesium and the amino acid taurine, and is designed to help ensure heart health.  Heart problems are rampant in North America and much of the world. Magnesium Taurate has the potential, backed up by extensive research, to help deal with heart problems and minimize the havoc they cause in people’s bodies and lives. Don’t let your heart go undernourished or unprotected. Let Magnesium Taurate help your heart regulate itself and bring you improved heart health.  By supplementing with this amino-acid / essential mineral combination, the body’s ability to avoid potentially debilitating deficiencies, stabilize cell membranes and inhibit the over-excitability of the central nervous system is synergistically enhanced.

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Research

Magnesium + Taurine: A Cardiovascular Combo
Recent studies have revealed that magnesium and taurine share a number of interchangeable and potentiating roles in human physiology. Studies have demonstrated that magnesium plays an important role in the metabolic regulation of taurine levels. Concurrently, taurine can fulfill magnesium’s biochemical functions in both overt and subclinical magnesium-deficient states. The four central areas where taurine and magnesium share common biological ground are: the ability to elicit overall improvements in cardiology, the potentiating effect on insulin sensitivity, the inhibitory effects on neuromuscular excitability, and the dependency on vitamin B6.

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Market Trends

Standalone magnesium supplements are very popular, especially among consumers looking to maintain or improve their heart health. It is well-known that typical North American diets are deficient in magnesium, and it is probably the most common mineral supplement used. It is not well-known, however, that taurine complements magnesiums roles, providing similar benefits and even making up for a magnesium deficiency in some ways.

AOR Advantage

This combination is based on compiled research showing that magnesium and taurine share many similar physiological functions especially in various cardioprotective effects, and that taurine can help fulfill the role of magnesium during deficiencies. AOR’s Magnesium Taurate provides a balanced amount of magnesium and taurine.

References

Ceremuzyński L, Gebalska J, Wolk R, Makowska E. Hypomagnesemia in heart failure with ventricular arrhythmias. Beneficial effects of magnesium supplementation. J Intern Med. 2000 Jan;247(1):78-86.

Finckenbeg P, et al. Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression. J Hypertens 2005 Feb;23(2):375-80.

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Reviews

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Abstracts

Dietary magnesium and DNA repair capacity as risk factors for lung cancer.
Carcinogenesis 2008 29(5):949-956.
Mahabir S, Wei Q, Barrera SL, Dong YQ, Etzel CJ, Spitz MR and Forman MR.

Magnesium (Mg) is required for maintenance of genomic stability; however, data on the relationship between dietary Mg intake and lung cancer are lacking. In an ongoing lung cancer case-control study, we identified 1139 cases and 1210 matched healthy controls with data on both diet and DNA repair capacity (DRC). Dietary intake was assessed using a modified Block-NCI food frequency questionnaire and DRC was measured using the host-cell reactivation assay to assess repair in lymphocyte cultures. After adjustment for potential confounding factors including DRC, the odds ratios (ORs) and 95% confidence intervals (CIs) for lung cancer with increasing quartiles of dietary Mg intake were 1.0, 0.83 (0.66-1.05), 0.64 (0.50-0.83) and 0.47 (0.36-0.61), respectively, for all subjects (P-trend < 0.0001). Similar results were observed by histology and clinical stage of lung cancer. Low dietary Mg intake was associated with poorer DRC and increased risk of lung cancer. In joint effects analyses, compared with those with high dietary Mg intake and proficient DRC, the OR (95% CI) for lung cancer in the presence of both low dietary Mg and suboptimal DRC was 2.36 (1.83-3.04). Similar results were observed for men and women. The effects were more pronounced among older subjects (>60 years), current or heavier smokers, drinkers, those with a family history of cancer in first-degree relatives, small cell lung cancer and late-stage disease. These intriguing results need to be confirmed in prospective studies.

 

Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients.
Br J Sports Med. 2006 Sep;40(9):773-8.
Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, Lettner K, Schmid P, Shechter M, Silver B, Bachl N.

BACKGROUND: Previous studies have demonstrated that in patients with coronary artery disease (CAD) upward deflection of the heart rate (HR) performance curve can be observed and that this upward deflection and the degree of the deflection are correlated with a diminished stress dependent left ventricular function. Magnesium supplementation improves endothelial function, exercise tolerance, and exercise induced chest pain in patients with CAD.
PURPOSE: We studied the effects of oral magnesium therapy on exercise dependent HR as related to exercise tolerance and resting myocardial function in patients with CAD.
METHODS: In a double blind controlled trial, 53 male patients with stable CAD were randomised to either oral magnesium 15 mmol twice daily (n = 28, age 61+/-9 years, height 171+/-7 cm, body weight 79+/-10 kg, previous myocardial infarction, n = 7) or placebo (n = 25, age 58+/-10 years, height 172+/-6 cm, body weight 79+/-10 kg, previous myocardial infarction, n = 6) for 6 months. Maximal oxygen uptake (VO2max), the degree and direction of the deflection of the HR performance curve described as factor k
RESULTS: Magnesium therapy for 6 months significantly increased intracellular magnesium levels (32.7+/-2.5 v 35.6+/-2.1 mEq/l, p
CONCLUSION: The present study supports the intake of oral magnesium and its favourable effects on exercise tolerance and left ventricular function during rest and exercise in stable CAD patients. 

 

Long-term outcome of intravenous magnesium therapy in thrombolysis-ineligible acute myocardial infarction patients.
Cardiology. 2003;99(4):205-10.
Shechter M, Hod H, Rabinowitz B, Boyko V, Chouraqui P.

The aim of our study was to analyze the long-term survival and cardiac function in 194 consecutive, thrombolysis-ineligible acute myocardial infarction (AMI) patients receiving 48-hour intravenous magnesium sulfate (22 g) – 96 patients, compared with placebo – 98 patients. After a mean 4.8-year follow-up, all-cause mortality and cardiac mortality were significantly lower in the magnesium compared to the placebo group [(18 vs. 33 patients, p < 0.01) and (12 vs. 30 patients, p < 0.001), respectively]. Rest radionuclide ventriculography tests for left-ventricular ejection fraction (LVEF) were assessed in surviving patients up to completion of follow-up. Magnesium-treated patients had a significantly higher LVEF (0.51 +/- 0.10 vs. 0.44 +/- 0.14, p < 0.05) and a lower incidence of heart failure compared to placebo-treated patients (12 vs. 3 patients, p = 0.02). Beneficial effects of intravenous magnesium therapy in thrombolysis-ineligible AMI patients appeared to last for at least 4.8 years, concomitant with preserved LVEF, suggesting a favorable role for acute magnesium treatment in these patients.

 

Hypomagnesemia in heart failure with ventricular arrhythmias. Beneficial effects of magnesium supplementation.
J Intern Med. 2000 Jan;247(1):78-86.
Ceremuzyński L, Gebalska J, Wolk R, Makowska E.

OBJECTIVE: To assess the role of electrolyte imbalance in cardiac arrhythmias associated with congestive heart failure.
DESIGN: Serum magnesium and potassium levels, urine magnesium excretion and the incidence of ventricular arrhythmias were assessed throughout the study. The patients who displayed complex arrhythmias after the first week of hospital medication were randomized 2:1 to double-blind magnesium supplementation or placebo.
SETTING: The study was carried out in one municipal hospital, providing primary care.
SUBJECTS: A total of 588 consecutive patients were screened for eligibility (clinical heart failure >/=6 months; NYHA class II-IV; left ventricular ejection fraction
INTERVENTIONS: Intravenous administration of magnesium (magnesium sulphate 8 g in 250 mL of 5% glucose) or placebo (250 mL of 5% glucose) over 12 h.
MAIN OUTCOME MEASURES: (i) Incidence of ventricular arrhythmias in patients with hypomagnesemia; (ii) effects of magnesium supplementation on ventricular arrhythmias.
RESULTS: On admission, hypomagnesemia was found in 38% and excessive magnesium loss in 72% of patients. Serum magnesium levels were lower and urine magnesium excretion was greater in patients with complex ventricular arrhythmias, both on admission and after treatment for heart failure. Intravenous administration of magnesium caused a significant decrease in the number of ventricular ectopic beats (P < 0.0001), couplets (P < 0.003) and episodes of nonsustained ventricular tachycardia (P < 0.01).
CONCLUSIONS: Hypomagnesemia, probably related to increased urine magnesium excretion, is an essential feature of heart failure associated with complex ventricular arrhythmias. These arrhythmias can be alleviated/abolished by magnesium supplementation.

 

Complementary vascular-protective actions of magnesium and taurine: a rationale for magnesium taurate.
Med Hypotheses. 1996 Feb;46(2):89-100.
McCarty MF.

By a variety of mechanisms, magnesium functions both intracellularly and extracellularly to minimize the cytoplasmic free calcium level, [Ca2+]i. This may be the chief reason why correction of magnesium deficiency, or induction of hypermagnesemia by parenteral infusion, exerts antihypertensive, anti-atherosclerotic, anti-arrhythmic and antithrombotic effects. Although the amino acid taurine can increase systolic calcium transients in cardiac cells (and thus has positive inotropic activity), it has other actions which tend to reduce [Ca2+]i. Indeed, in animal or clinical studies, taurine lowers elevated blood pressure, retards cholesterol-induced atherogenesis, prevents arrhythmias and stabilizes platelets–effects parallel to those of magnesium. The complex magnesium taurate may thus have considerable potential as a vascular-protective nutritional supplement, and might also be administered parenterally, as an alternative to magnesium sulfate, in the treatment of acute myocardial infarction as well as of pre-eclampsia. The effects of magnesium taurate in diabetes deserve particular attention, since both magnesium and taurine may improve insulin sensitivity, and also may lessen risk for the micro- and macrovascular complications of diabetes.